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Target Organs and Levels of Evidence for TR-144

Bioassay of 2-Aminoanthraquinone for Possible Carcinogenicity (CASRN 117-79-3)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
2-Aminoanthraquinone
117-79-3
06/29/1978Dye intermediate for dyes used in paints and other pigmentsDosed-Feed
FR: 0,.2 (AVG), MR: 0,.35,.69 (AVG), M: 0,.5,1.0 %/50 PER GROUP
T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (NEOPLASTIC NODULE OR CARCINOMA)
Female Rats: Inadequate Study
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (CARCINOMA)
  • Hematopoietic System: (LYMPHOMA)