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Target Organs and Levels of Evidence for TR-146

Bioassay of Nithiazide for Possible Carcinogenicity (CASRN 139-94-6)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Nithiazide
139-94-6
10/25/1978Antiprotozoal compound in veterinary medicine.Dosed-Feed
R: 0,625,1250, M: 0,2500,5000 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Mammary Gland: (FIBROADENOMA OR CYSTADENOMA)
  • Skin: (FIBROADENOMA OR CYSTADENOMA)
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (ADENOMA OR CARCINOMA)
Female Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: (ADENOMA OR CARCINOMA)