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Target Organs and Levels of Evidence for TR-159

Bioassay of Phthalic Anhydride for Possible Carcinogenicity (CASRN 85-44-9)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Phthalic anhydride
85-44-9
12/13/1978Resins; plasticizers; polyesters; synthesis of dyes; drug intermediate; lab reagent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
R: 0,7500,15000, MM: 0,16346,32692 (AVG), FM: 0,12019,24038 (AVG) PPM/50 PER GROUP
Frederick Cancer Research Facility

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Negative
Female Mice: Negative