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Target Organs and Levels of Evidence for TR-164

Bioassay of N-Nitrosodiphenylamine for Possible Carcinogenicity (CASRN 86-30-6)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
N-Nitrosodiphenylamine
86-30-6
12/13/1978Anti-scorching agent, intermediate, stabilizer, rubber additive (HSDB 1990)Dosed-Feed
R: 0,1000,4000, MM: 0,10000,20000, FM: 0,2315,5741 (AVG) PPM/50 PER GROUP
Frederick Cancer Research Facility

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL CARCINOMA)
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL CARCINOMA)
Male Mice: Negative
Female Mice: Negative