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Target Organs and Levels of Evidence for TR-179

Bioassay of p-Quinone Dioxime for Possible Carcinogenicity (CASRN 105-11-3)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
p-Benzoquinone dioxime
105-11-3
10/25/1978Vulcanization of rubberDosed-Feed
R: 0,375,750, M: 0,750,1500 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Urinary Bladder: (TRANSITIONAL CELL PAPILLOMA OR CARCINOMA OR SQUAMOUS CELL CARCINOMA)
Male Mice: Negative
Female Mice: Negative