National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/8417

Target Organs and Levels of Evidence for TR-187

Bioassay of 5-Chloro-o-toluidine for Possible Carcinogenicity (CASRN 95-79-4)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
5-Chloro-o-toluidine
95-79-4
10/25/1978Dye intermediateDosed-Feed
R: 0,2500,5000, M: 0,2000,4000 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Vascular System (Unspecified): HEMANGIOSARCOMA
  • Liver: CARCINOMA
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Vascular System (Unspecified): HEMANGIOSARCOMA
  • Liver: CARCINOMA


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