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Target Organs and Levels of Evidence for TR-207

Carcinogenesis Bioassay of Cytembena (CASRN 21739-91-3)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Cytembena
21739-91-3
06/27/1980Cytostatic agent (formerly)Intraperitoneal Injection
R: 0,7,14, M: 0,12,24 MG/KG/50 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Mesothelium (Abdominal Cavity/Tunica Vaginalis): MESOTHELIOMA 0/50 37/50 36/50
Female Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Mammary Gland: FIBROADENOMA 13/49 22/50 36/50
Male Mice: Negative
Female Mice: Negative