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Target Organs and Levels of Evidence for TR-216

Carcinogenesis Bioassay of 11-Aminoundecanoic Acid (CASRN 2432-99-7) in F344 Rats and B6C3F1 Mice

Chemical (Study Title)
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
11-Aminoundecanoic acid
02/18/1981Monomer for nylon 11Dosed-Feed
0,7500,15000 PPM/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Liver: NEOPLASTIC NODULE 1/50 9/50 8/50
  • Urinary Bladder: TRANSITIONAL CELL CARCINOMA 0/48 0/48 7/49
Female Rats: Negative
Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: LYMPHOMA 2/50 9/50 4/50
Female Mice: Negative