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Target Organs and Levels of Evidence for TR-221

Carcinogenesis Bioassay of Locust Bean Gum (CASRN 9000-40-2) in F344 Rats and B6C3F1 Mice (Feed Study)

Chemical (Study Title)
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Locust bean gum
10/15/1980Stabilizer, thickener, binder in foods & cosmetics, pharmaceutic agent, in paints, in treatment of diarrhea (Merck). Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
0,25000,50000 PPM/50 PER GROUP
T.S.I. Mason Laboratories, Inc.

Levels of Evidence

Male Rats: Negative
Female Rats: Negative
Male Mice: Negative
Female Mice: Negative