Target Organs and Levels of Evidence for TR-236
Carcinogenesis Bioassay of D-Mannitol (CASRN 69-65-8) in F344/N Rats and B6C3F1 Mice (Feed Study)
Chemical (Study Title) CASRN | Peer Review Date | Primary Uses | Route/Exposure Levels | Study Laboratory |
---|---|---|---|---|
D-Mannitol 69-65-8 | 12/16/1981 | Chewable tablets, sugar replacement, candies and gums, osmotic diuretic, and fluid replacement. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products. | Dosed-Feed 0,25000,50000 PPM/50 PER GROUP | Southern Research Institute |