National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/7158

Target Organs and Levels of Evidence for TR-242

Carcinogenesis Bioassay of Diallyl Phthalate (CASRN 131-17-9) in B6C3F1 Mice (Gavage Study)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Diallyl phthalate
131-17-9
06/16/1982Forms laminates with various fillers (e.g. Glass cloth). Electrical insulation. Dye carrier. Primary plasticizer.Gavage
0,150,300 MG/KG/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: SQUAMOUS CELL PAPILLOMA 0/49 1/47 2/49
  • Hematopoietic System: LYMPHOMA 6/50 5/50 12/50
Non-Neoplastic Lesions
  • FORESTOMACH: INFLAMMATION, CHRONIC; HYPERPLASIA
Female Mice: Equivocal
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Forestomach: SQUAMOUS CELL PAPILLOMA 0/48 1/47 2/49
Non-Neoplastic Lesions
  • FORESTOMACH: INFLAMMATION, CHRONIC; HYPERPLASIA


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