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Target Organs and Levels of Evidence for TR-246

Lifetime Carcinogenesis Studies of Chrysotile Asbestos (CASRN 12001-29-5) in Syrian Golden Hamsters (Feed Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Asbestos, chrysotile(IR)
12001-29-5
06/23/1981Asbestos, chrysotile: asbestos cement. Textiles. Insulation. Friction products. Fireproofing agent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
0,1 %/60 PER GROUP
IIT Research Institute

Levels of Evidence

Male Hamsters: Negative
Female Hamsters: Negative


Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Asbestos, chrysotile(IR) + Dimethyl hydrazine
12001-29-5
06/23/1981Asbestos, chrysotile: asbestos cement. Textiles. Insulation. Friction products. Fireproofing agent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
0,1 %/60 PER GROUP
IIT Research Institute

Levels of Evidence

Male Hamsters: Inadequate
Female Hamsters: Inadequate


Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Asbestos, chrysotile(SR)
12001-29-5
06/23/1981Asbestos, chrysotile: asbestos cement. Textiles. Insulation. Friction products. Fireproofing agent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
0,1 %/60 PER GROUP
IIT Research Institute

Levels of Evidence

Male Hamsters: Negative
Female Hamsters: Negative