Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:
https://ntp.niehs.nih.gov/go/7590

Target Organs and Levels of Evidence for TR-253

Carcinogenesis Studies of Allyl Isovalerate (CASRN 2835-39-4) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Allyl isovalerate
2835-39-4
09/22/1982Fragrance in cosmetics, flavoring agent in foodsGavage
0,31,62 MG/KG/50 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: LEUKEMIA 1/50 4/50 7/50
Female Rats: Negative
Male Mice: Negative
Female Mice: Positive
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Hematopoietic System: LYMPHOMA 11/50 11/50 18/50