https://ntp.niehs.nih.gov/go/LOE-TR-273

Target Organs and Levels of Evidence for TR-273

Toxicology and Carcinogenesis Studies of Trichloroethylene (CASRN 79-01-6) in Four Strains of Rats (ACI, August, Marshall, Osborne-Mendel) (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Trichloroethylene
79-01-6
08/19/1986 Gavage
0,500,1000 MG/KG/50 PER GROUP
Papanicolaou Research Institute

Levels of Evidence

Male Rats: Inadequate Study
Type Organ/Tissue (Lesion)
Note
  • DESPITE THESE LIMITATIONS, TUBULAR CELL NEOPLASMS OF THE KIDNEY WERE OBSERVED IN RATS EXPOSED TO TRICHLOROETHYLENE AND INTERSTITIAL CELL NEOPLASMS OF THE TESTIS WERE OBSERVED IN MARSHALL RATS EXPOSED TO TRICHLOROETHYLENE.
Female Rats: Inadequate Study
 
Chemical (Study Title)
CASRN
Peer Review Date Route/Exposure Levels Study Laboratory
Trichloroethylene
79-01-6
08/19/1986 Gavage
0,500,1000 MG/KG/50 PER GROUP
Papanicolaou Research Institute

Levels of Evidence

Male Rats: Inadequate Study
Type Organ/Tissue (Lesion)
Note
  • DESPITE THESE LIMITATIONS, TUBULAR CELL NEOPLASMS OF THE KIDNEY WERE OBSERVED IN RATS EXPOSED TO TRICHLOROETHYLENE AND INTERSTITIAL CELL NEOPLASMS OF THE TESTIS WERE OBSERVED IN MARSHALL RATS EXPOSED TO TRICHLOROETHYLENE.
Female Rats: Inadequate Study