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Target Organs and Levels of Evidence for TR-279

Toxicology and Carcinogenesis Studies of Amosite Asbestos (CASRN 12172-73-5) in F344/N Rats (Feed Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Asbestos, amosite
12172-73-5
09/22/1982Asbestos-cement building products. Fire-resistant insulation products. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
0,1 %/250 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Negative
Female Rats: Negative


Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Asbestos, amosite + Dimethyl hydrazine
12172-73-5
09/22/1982Asbestos, chrysotile: asbestos cement. Textiles. Insulation. Friction products. Fireproofing agent. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Dosed-Feed
0,1% /250 PER GROUP
Hazleton, Vienna

Levels of Evidence

Male Rats: Inadequate Study
Female Rats: Inadequate Study