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https://ntp.niehs.nih.gov/go/9626

Target Organs and Levels of Evidence for TR-293

Toxicology and Carcinogenesis Studies of HC Blue No. 2 [2,2'-((4-((2-Hydroxyethyl)amino)-3-nitrophenyl)imino)bis(ethanol)] (CASRN 33229-34-4) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
HC blue 2
33229-34-4
07/27/1984Dye in semi-permanent hair dyes. Dosed-Feed
MR&MM: 0,5000,10000, FR&FM: 0,10000,20000 PPM/50 PER GROUP
Southern Research Institute

Levels of Evidence

Male Rats: No Evidence
TypeOrgan/Tissue (Lesion)
Non-Neoplastic Lesions
  • SKULL: HYPEROSTOSIS
Female Rats: No Evidence
TypeOrgan/Tissue (Lesion)
Non-Neoplastic Lesions
  • SKULL: HYPEROSTOSIS
Male Mice: No Evidence
Female Mice: No Evidence