National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/9632

Target Organs and Levels of Evidence for TR-296

Toxicology and Carcinogenesis Studies of Tetrakis(hydroxymethyl)phosphonium sulfate (THPS) (CASRN 55566-30-8) and Tetrakis(hydroxymethyl)phosphonium chloride (THPC) (CASRN 124-64-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Tetrakis(hydroxymethyl)phosphonium chloride
124-64-1
03/26/1986Flame retardant for textiles. Broad spectrum disinfectant. Chemical intermediate. Gavage
R: 0,3.75,7.5, MM: 0,7.5,15, FM: 0,15,30 MG/KG/50 PER GROUP
Battelle Columbus Laboratory

Levels of Evidence

Male Rats: No Evidence
Female Rats: No Evidence
Male Mice: No Evidence
Female Mice: No Evidence


Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Tetrakis(hydroxymethyl)phosphonium sulfate
55566-30-8
03/26/1986Flame retardant for textiles. Broad spectrum disinfectant. Chemical intermediate.Gavage
0, 5, 10 MG/KG/50 PER GROUP
Battelle Columbus Laboratory

Levels of Evidence

Male Rats: No Evidence
Female Rats: No Evidence
Male Mice: No Evidence
Female Mice: No Evidence


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