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Target Organs and Levels of Evidence for TR-310

Toxicology and Carcinogenesis Studies of Marine Diesel Fuel and JP-5 Navy Fuel (CASRN 8008-20-6) in B6C3F1 Mice (Dermal Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Diesel fuel marine
DIESELFUEL
08/14/1985Used in illuminating fuels, motor and jet fuels. Heating fuel. In paint thinners. Vehicle for insecticides and fungicides. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Topical Application
FR: 0,300,600, MR: 0,150,300, M: 0,250,500 MG/KG/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Mice: Equivocal Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Skin: SQUAMOUS CELL PAPILLOMA 0/49 0/49 1/49; SQUAMOUS CELL CARCINOMA 0/49 0/49 2/49
Female Mice: Equivocal Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Skin: SQUAMOUS CELL CARCINOMA 0/50 1/45 2/48


Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Navy fuels JP-5
8008-20-6
08/14/1985Used in illuminating fuels, motor and jet fuels. Heating fuel. In paint thinners. Vehicle for insecticides and fungicides. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products.Topical Application
0,250,500 MG/KG/50 PER GROUP
Litton Bionetics, Inc.

Levels of Evidence

Male Mice: No Evidence
Female Mice: No Evidence