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Target Organs and Levels of Evidence for TR-317

Toxicology and Carcinogenesis Studies of Chlorpheniramine Maleate (CASRN 113-92-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
Chlorpheniramine maleate
113-92-8
12/09/1985AntihistamineGavage
MR: 0,15,30 MG/KG, FR: 0,30,60 MG/KG, MM: 0,25,50 MG/KG, FM: 0,100,200 MG/KG/50 PER GROUP
Battelle Columbus Laboratory

Levels of Evidence

Male Rats: No Evidence
Female Rats: No Evidence
Male Mice: No Evidence
Female Mice: No Evidence
TypeOrgan/Tissue (Lesion)
Non-Neoplastic Lesions
  • THYROID GLAND: CYSTS, FOLLICULAR CELL; HYPERPLASIA, FOLLICULAR CELL