Target Organs and Levels of Evidence for TR-326
Toxicology and Carcinogenesis Studies of Ethylene Oxide (CASRN 75-21-8) in B6C3F1 Mice (Inhalation Studies)
| Chemical (Study Title) CASRN | Peer Review Date | Primary Uses | Route/Exposure Levels | Study Laboratory |
|---|---|---|---|---|
| Ethylene oxide 75-21-8 | 08/19/1986 | Accelerates ripening in fruit and maturing of tobacco leaves. Fungistat. Rocket propellant. Fumigant for foodstuffs and textiles. Organic synthesis. Sterilize surgical instruments. Chemical intermediate. Associated with tobacco: reported either as a natural component of tobacco, pyrolysis product (in tobacco smoke), or additive for one or more types of tobacco products. | Inhalation 0,50,100 PPM/50 PER GROUP | Battelle Northwest Laboratory |
Levels of Evidence
Male Mice: Clear Evidence
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|
Female Mice: Clear Evidence
| Type | Organ/Tissue (Lesion) |
|---|---|
| Neoplastic Lesions |
|