National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/13736

Target Organs and Levels of Evidence for TR-330

Toxicology and Carcinogenesis Studies of 4-Hexylresorcinol (CASRN 136-77-6) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
4-Hexylresorcinol
136-77-6
03/04/1987Anthelmintic, topical antiseptic.Gavage
0,62.5,125 MG/KG/50 PER GROUP
Physiological Research Laboratory

Levels of Evidence

Male Rats: No Evidence
Female Rats: No Evidence
Male Mice: Equivocal Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Adrenal Gland Medulla: PHEOCHROMOCYTOMA 1/50 2/50 5/49
  • Harderian Gland: ADENOMA 0/50 0/50 1/50 OR CARCINOMA 0/50 4/50 2/50 COMBINED 0/50 4/50 3/50
Female Mice: No Evidence


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