Share This:
https://ntp.niehs.nih.gov/go/13754

Target Organs and Levels of Evidence for TR-339

Toxicology and Carcinogenesis Studies of 2-Amino-4-Nitrophenol (CASRN 99-57-0) in F344/N Rats and B6C3F1 Mice (Gavage Studies)

Chemical (Study Title)
CASRN
Peer Review DatePrimary UsesRoute/Exposure LevelsStudy Laboratory
2-Amino-4-nitrophenol
99-57-0
07/14/1987Intermediate for dyes; in hair dyesGavage
0,125,250 MG/KG/50 PER GROUP
Physiological Research Laboratory

Levels of Evidence

Male Rats: Some Evidence
TypeOrgan/Tissue (Lesion)
Neoplastic Lesions
  • Kidney Tubular Cell: ADENOMA 0/50 1/48 3/50
Non-Neoplastic Lesions
  • KIDNEY: HYPERPLASIA, TUBULAR CELL 1/50 4/48 5/50
Female Rats: No Evidence
Male Mice: No Evidence
Female Mice: No Evidence