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Target Organs and Levels of Evidence for TR-556

Toxicology and Carcinogenesis Studies of Chromium Picolinate Monohydrate (CASRN 27882-76-4) in F344/N Rats and B6C3F1 Mice (Feed Studies)

Chemical (Study Title)
Peer Review Date Primary Uses Route/Exposure Levels Study Laboratory
Chromium picolinate monohydrate
02/27/2008 Used as a dietary supplement for losing weight Dosed-Feed
R&M: 0, 2000, 10000, OR 50000 PPM; 50/SEX/SPECIES/DOSE
Southern Research Institute

Levels of Evidence

Male Rats: Equivocal Evidence
Type Organ/Tissue (Lesion)
May Have Been Related
  • Preputial Gland: Adenoma 1/50 1/50 7/50 4/50
Female Rats: No Evidence
Male Mice: No Evidence
Female Mice: No Evidence