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Nomination Summary for Gum guggul and Some of its Steroidal Constituents (N20333)

Nominated Substances: Guggulsterone, E-guggulsterone, Z-Guggulsterone, Gum Guggul Extract

Nomination Date: 04/15/2003

Nominator: NIEHS

Rationale: Consumer exposure through increasing dietary supplement use; demonstrated metabolic and hormonal effects; lack of adequate toxicological data

NTP Principles: 5, 6

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: GUMGUGGULEXT

Agent Name: Gum Guggul Extract