Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Nomination Summary for Oxazepam (N84333)

Nominated Substances: Oxazepam

Nomination Date: 03/10/1986

Nominator: FDA

Rationale: Oxazepam is a metabolite of most benzodiazepines marketed. These drugs are among the most often prescribed in medicine and have been used primarily as antianxiety/hypnotics for many years. Most have some carcinogenicity studies, but none have complete two species bioassays similar to protocols currently followed by the NTP. Increased incidences of tumors in rats exposed to these drugs has been observed. However, it is not known whether the types of tumors observed are specific for each chemical or characteristic of certain benzodiazepine compounds.

NTP Principles: Pre 1993 - 3, 4


Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.


CASRN: 604-75-1

Agent Name: Oxazepam