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Nomination Summary for Dimethylformamide (N85204)

Nominated Substances: Dimethylformamide

Nomination Date: 06/05/1984

Nominator: NIOSH

Rationale: Dimethylformamide (DMF) is widely used as a solvent and most commonly used in the manufacture of polymers, protective coatings, adhesives, films and printing inks. This wide application, coupled with its volatility and its ability to readily penetrate intact skin, denotes that DMF may pose significant health hazards to man during its manufacture, distribution, and use. The experimental data is inadequate. Reports from teratological studies report no fetal malformations but can produce increased fetal deaths when the doses approach the lethal level for the female parent of the species.

NTP Principles: not specified

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

CASRN: 68-12-2

Agent Name: Dimethylformamide