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Nomination Summary for Styrene (N85307)

Nominated Substances: Styrene

Nomination Date: 11/21/1984

Nominator: California Department of Health Services

Rationale: Large number of workers exposed via inhalation at potentially high dose levels; adequate evidence of mutagenicity for styrene; clear evidence of mutagenicity and carcinogenicity for styrene-7,8-oxide, a metabolite of styrene; presence of metabolic activation system in lung.

NTP Principles: Pre 1993 - 3, 4, 5, 8

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

CASRN: 100-42-5

Agent Name: Styrene