Nomination Summary for Styrene (N85307)
Nominated Substances: Styrene
Nomination Date: 11/21/1984
Nominator: California Department of Health Services
Rationale: Large number of workers exposed via inhalation at potentially high dose levels; adequate evidence of mutagenicity for styrene; clear evidence of mutagenicity and carcinogenicity for styrene-7,8-oxide, a metabolite of styrene; presence of metabolic activation system in lung.
NTP Principles: Pre 1993 - 3, 4, 5, 8
Agents and Status
The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.
Agent Name: Styrene