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Nomination Summary for Perfluorinated compounds (N90211)

Nominated Substances: Perfluorobutyric acid, Perfluorodecanoic acid (PFDA), Perfluorooctane, Perfluorooctanoic acid (PFOA)

Nomination Date: 09/03/1990

Nominator: Japan National Institute of Health Sciences (NIHS)

Rationale: Perfluorinated compounds are potent peroxisome proliferators and found to induce 8-hydroxydeoxyguanosine in the livers of treated rats as in the case of phthalic ester compounds.

NTP Principles: not specified

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 335-76-2

Agent Name: Perfluorodecanoic acid (PFDA)

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CASRN: 335-67-1

Agent Name: Perfluorooctanoic acid (PFOA)