Nomination Summary for Chlorohydrins (N97023)
Nomination Date: 09/02/1997
Nominator: Private Individual
Rationale: Human epidemiology studies (Benson & Teta in British Journal of Industrial Medicine 50: 710-16, 1993) have shown an association between exposure to chlorohydrins and pancreatic lesions. In the NTP 13-week studies, pancreatic lesions were detected in rodents. However, the 2-year studies were conducted at levels below the dose at which the 13-week lesions were seen.
NTP Principles: not specified