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Nomination Summary for Cubebene (N98014)

Nominated Substances: alpha-Cubebene

Nomination Date: 02/18/1998

Nominator: NCI

Rationale: alpha-Cubebene is a naturally occurring product with no reported uses. However, the essential oils in which it occurs are used in pharmaceuticals, cosmetics, food products, folk medicines and insect attractants. No information on the toxicity of alpha-cubebene was found. The structure of alpha-cubebene suggests that possible metabolites might be more reactive than the parent compound. NCI is nominating alpha-cubebene for metabolic studies to determine whether any further evaluation of the compound is warranted.

NTP Principles: not specified

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