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ICCVAM Biennial Report 2020-2021

Biennial Progress Report 2020-2021 Interagency Coordinating Committee on the Validation of Alternative Methods

Integrated Chemical Environment Data Updates

NICEATM's Integrated Chemical Environment (ICE) provides data and tools to help develop, assess, and interpret chemical safety tests. Updates to ICE data sets during 2020 and 2021 provided additional metadata in downloads of query results, updated curated HTS data, and new data in these areas:

  • Skin irritation: in vivo and in vitro data.
  • Cancer/genotoxicity: reference chemical lists and in vitro and in vivo data.
  • Developmental and reproductive toxicity: in vivo data.
  • Skin sensitization: data from human predictive patch tests.
  • Chemical property predictions from OPERA.