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Abbreviations Used in the Management Status Report

Route of Administration
AQUAT Aquatic IV Intravenous
CAPS Per os (Capsule) IVAG Intravaginal
DERMAL Dermal IVOR IV Injection and Oral
FEED Dosed-Feed MICRO Microencapsulation in Feed
GAV Gavage MULTI Multiple Routes
GAV/WATER Gavage & Dosed-Water N/A Not Applicable
GV/WB Gavage, Whole Body Exposure OTHER Other
IC/IJ IC Injection SC&GV Subcutaneous Injection and Gavage
ID/CN Intraductal Cannulation SC/IJ Subcutaneous Injection
IM Intramuscular SP Topical Application
INHAL Inhalation UD Not Currently Entered
IP/IJ Intraperitoneal Injection UTERO In Utero
IP/OT IP Inj/Orotracheal WATER Dosed-Water
IT Intratracheal WB Whole Body Exposure
Note: Dermal, skin application, and skin paint are synonymous. Different terms were used at different times.

Species: Strain
C Chicks HU Human (Cell Lines)
D Dogs M Mice
DL Drosophila MO Monkeys
F Fish R Rats
FR Frog RA Rabbits
GP Guinea Pigs RM Rats/Mice
H Hamsters
NA Chicks:Not Available ML Mice:Tg.Lac1/C57BL/6 (Big Blue)
NA Dogs:Not Available MM Mice:BALB/cByJ
O3 Dogs:Beagles MN Mice:Tg.AC (FVB/N) Homozygous
NA Drosophila:Not Available MO Mice:CB6F1
F1 Fish:Medaka (Oryzias latipes) MP Mice:C57BL/6-APC+/APC-1638N (Tg:APC)
F2 Fish:Guppy (Poecilia reticulata) MQ Mice:P16(Ink4a)/(+/-) (C57BL/6)
F3 Fish:Zebra (Danio rerio) MR Mice:129S1/SvImJ
NA Fish:Not Available MS Mice:P53 +/- (FVB/N)
NA Frog:Not Available MT Mice:SKH-1 Hairless
NA Guinea Pigs:Not Available MU Mice:TRAMP (C57BL/6 PB-TAG TRANSGENE)
O6 Guinea Pigs:Hartley MV Mice:B6C3F1 (NCTR)
H1 Hamsters:Syrian Golden MW Mice:BALB/c
NA Hamsters:Not Available MX Mice:AM3 (C57BL/6)
TK6HG2 Human (Cell Lines):TK6 and HepG2 Cells MY Mice:CD-1 Reg.[Crl:CD1(ICR)]
129B6TRP53 Mice:Female 129S1.SvlmJ crossed to B6.129- Trp53<tm1Brd> males homozygous for the Trp53 null allele MZ Mice:C57BL/6J (Jackson)
60 Mice:NOD. B10Sn-H2(b)/J NA Mice:Not Available
61 Mice:NZO/HiLtJ RB6TRP53 Mice:Female BTBR.Tj (R) crossed to B6.129- Trp53<tm1Brd> males homozygous for the Trp53 null allele
62 Mice:PWK/PhJ NA Monkeys:Not Available
63 Mice:B6C3F1/J (Jackson) RH Monkeys:Rhesus
AB6TRP53 Mice:Female A/J crossed to B6.129-Trp53<tm1Brd> males homozygous for the Trp53 null allele 44 Rats:Sprague Dawley (NCTR)
B6129 Mice:B6.129-Trp53<TM1BRD> 48 Rats:Crl:CD (SD)
C3B6 Mice:C3B6.129F1-Trp53<TM1BRD> F344 Rats:Fischer 344
C3B6TRP53 Mice:Female C3H/HeJ crossed to B6.129- Trp53<tm1Brd> males homozygous for the Trp53 null allele FSAS Rats:F344/NCrl (SAS FISCH)
C6N Mice:C57BL/6N HSD Rats:Harlan Sprague-Dawley
CB6TRP53 Mice:Female Balb/c (C) crossed to B6.129- Trp53<tm1Brd> males homozygous for the Trp53 null allele HSDD Rats:Harlan Sprague Dawley (Dublin Facility)
D2B6TRP53 Mice:Female DBA2/J (D2) crossed to B6.129- Trp53<tm1Brd> males homozygous for the Trp53 null allele HSDE Rats:Hsd:Sprague Dawley SD
DOJ Mice:Diversity Outbred (Jackson) HSDI Rats:Harlan Sprague Dawley (Indianapolis Facility)
M0 Mice:SKH-1 Hairless (NCTR) ML Rats:Tg.Lac1/C57BL/6 (Big Blue)
M1 Mice:C57BL/6 NA Rats:Not Available
M11 Mice:CAST/EiJ (M. m. castaneus) R1 Rats:Osborne Mendel
M14 Mice:WSB/EiJ (M. m. domesticus) R10 Rats:F344/N Charles River
M15 Mice:C3H/HeJ R2 Rats:F344/N
M2 Mice:C3H R3 Rats:ACI
M22 Mice:B6C3F1/N R4 Rats:August
M3 Mice:B6C3F1 R5 Rats:Long-Evans
M4 Mice:Swiss R6 Rats:Marshall
M5 Mice:Swiss CD-1 R7 Rats:Sherman
M6 Mice:Swiss Webster R8 Rats:Sprague Dawley
M7 Mice:Sencar R9 Rats:Wistar
M8 Mice:MMTV/RAS (Tg.SH) RA Rats:CD
M9 Mice:MMTV/MYC (Tg.M) RB Rats:NCI Black Reiter (NBR)
MA Mice:MMTV/NEU (Tg.Nk) RC Rats:F344 (NCTR)
MB Mice:NIH Swiss RC1 Rats:F344/N (NCTR)
MC Mice:PIM RD Rats:F344/NTac
MCBA Mice:CBA/ Ca Jackson RE Rats:Wistar Han
MD Mice:P53 +/- (C57BL/6) ZL Rats:Zucker - Lean (HsdHlr:ZUCKER-Lepr+)
ME Mice:Tg.AC (FVB/N) Hemizygous ZLC Rats:Zucker - Lean (Charles River)
MF Mice:A/J ZO Rats:Zucker - Obese (HsdHlr:ZUCKER-Leprfa)
MG Mice:B6.SJL-Ptprc[a] Pepc[b]/BoyJ ZOC Rats:Zucker - Obese (Charles River)
MH Mice:Tg/RASH2/CB6F1 NA Rabbits:Not Available
MI Mice:FVB/N NA Rats/Mice:Not Available
MJ Mice:C3B6F1-+/TRP53<TM1BRD> (NCTR) R2 Rats/Mice:F344/N
MK Mice:CB6F1-Tg(HRAS)2Jic [(BALB/cByJTac x C57BL/6JTac)-Tg(HRAS)2Jic F1