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Testing Status of Libby Amphibole 2007 09075


Short-Term Toxicity

  • 7 months (Inhalation)  (C09075)  On Test 
    • Rats: Harlan Sprague-Dawley
    • Dose: 0, 0.1, 0.3, 1, 3, 10 mg/m3; n=35 males/exposure concentration or n=50 females/exposure concentration.

Long-Term Carcinogenicity

  • 2 years (Inhalation)  (C09075B)  On Test 
    • Chronic exposure: Continuous exposure or CxT exposure
    • Rats: Hsd:Sprague Dawley SD
    • Dose: (chronic) 0, 0.1, 0.3, 1, 3, 10 mg/m3. (continuous exposure) 0, 0.1, 0.3, 1, 3, 10 mg/m3; n=89 sex/exposure concentration (CxT exposure) 3 mg/m3; n=79 males exposed for 2.4 months, 69 males exposed for 8 months.