Testing Status of Methyl ethyl ketone peroxide 10001-N
CASRN: 1338-23-4
Formula: C8-H14-O4
Synonyms/Common Names
- 2-Butanone, peroxide
Short-Term Toxicity
- 2 weeks (Topical Application)
(C55447B)
Completed
- TOX-18 (NIH Number: 93-3341)
(Peer Review Approval 06/24/1992A )
Toxicity Studies of Methyl Ethyl Ketone Peroxide (CASRN 1338-23-4) in Dimethyl Phthalate (CASRN 131-11-3) (45:55) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0, 50.6, 101.3, 202.5, 405, OR 810 MG/KG; M: 0, 112.5, 225, 450, 900, OR 1800 MG/KG (5/S/S).
- TOX-18 (NIH Number: 93-3341)
(Peer Review Approval 06/24/1992A )
- 13 weeks (Topical Application)
(C55447B)
Completed
- TOX-18 (NIH Number: 93-3341)
Toxicity Studies of Methyl Ethyl Ketone Peroxide (CASRN 1338-23-4) in Dimethyl Phthalate (CASRN 131-11-3) (45:55) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0, 1.07, 3.57, 10.7, 35.7, OR 107 MG/ANIMAL; M: 0, 0.357, 1.19, 3.57, 11.9, OR 35.7 MG/ANIMAL (10/S/S).
- TOX-18 (NIH Number: 93-3341)
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(774268)
Completed
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Positive
- Micronucleus
(A70805)
Completed
- Citation: Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194
- Mice: B6C3F1
- Male Negative
- Female Negative
- Mouse Lymphoma
(091264)
Completed
- Mice
- Positive
- Salmonella
(594981)
Completed
- Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
- Negative
- Salmonella
(784039)
Completed
- Positive