Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of D-Carvone 10093-S

 

CASRN: 2244-16-8

Formula: C10-H14-O

Synonyms/Common Names

  • 2-Methyl-5-(1-methylethenyl)-2-cyclohexen-1-one

Short-Term Toxicity

  • 14-Day (Gavage)  (C55867A)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Gavage)  (C55867A)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 93, 1500 MG/KG/30 MALES PER GROUP/10 FEMALES PER GROUP.

Long-Term Carcinogenicity

  • 2 years (Gavage)  (C55867A)  Completed 
    • TR-381 (NIH Number: 90-2836)  (Peer Review Approval 06/27/1989A )
      Toxicology and Carcinogenesis Studies of d-Carvone (CASRN 2244-16-8) in B6C3F1 Mice (Gavage Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Carcinogenesis Results
      • Male Mice No Evidence 
      • Female Mice No Evidence 
    • Dose: R: 0, 175, 375, M: 0, 375, 750 MG/KG/50 PER GROUP.

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (983543)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Salmonella  (544172)  Completed 
    • Citation: Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
    •  Negative