Testing Status of Hexachloroethane 10126-E
CASRN: 67-72-1
Related: HALOGENATED ETHANES CS (HAXACHLOROETHANE)
Formula: C2-Cl6
Synonyms/Common Names
- Carbon hexachloride
Short-Term Toxicity
- 14-Day (Gavage)
(C04604A)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- 14-Day (Gavage)
(C04604B)
Completed
- Rats: F344/N
- 13-Week (Gavage)
(C04604A)
Completed
- Rats: Osborne Mendel; Mice: B6C3F1
- Dose: R: 0, 178, 1780, M: 0, 316, 3160 MG/KG/5 PER GROUP.
- 13-Week (Gavage)
(C04604B)
Completed
- Rats: F344/N
- Dose: 0, .047, .750 G/KG/10 PER GROUP.
Long-Term Carcinogenicity
- 2-Year (Gavage)
(C04604A)
Completed
- TR-068 (NIH Number: 78-1318)
(Peer Review Approval 01/18/1978A )
Bioassay of Hexachloroethane for Possible Carcinogenicity (CASRN 67-72-1) - Rats: Osborne Mendel; Mice: B6C3F1
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Positive
- Female Mice Positive
- Dose: R: 0, 212, 423 M:0, 590, 1179 MG/KG/50 PER GROUP.
- TR-068 (NIH Number: 78-1318)
(Peer Review Approval 01/18/1978A )
- 2 years (Gavage)
(C04604B)
Completed
- TR-361 (NIH Number: 89-2816)
(Peer Review Approval 10/03/1988A )
Toxicology and Carcinogenesis Studies of Hexachloroethane (CASRN 67-72-1) in F344/N Rats (Gavage Studies) - Rats: F344/N
- Carcinogenesis Results
- Male Rats Clear Evidence
- Female Rats No Evidence
- Dose: MR: 0, 10, 20, FR: 0, 80, 160 MG/KG/50 PER GROUP.
- TR-361 (NIH Number: 89-2816)
(Peer Review Approval 10/03/1988A )
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(415312)
Completed
- Citation: Galloway, S., Armstrong, M., Reuben, C., Colman, S., Brown, B., Cannon, C., Bloom, A., Nakamura, F., Ahmed, M., Duk, S., Rimpo, J., Margolin, B., Resnick, M., Anderson, B., and Zeiger, E. Chromosome aberration and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ. Molec. Mutagen. Vol. 10 (Suppl 10) (1987) 1-176
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Negative
- Salmonella
(188925)
Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Negative
- Salmonella
(248997)
Completed
- Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
- Negative