Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.


The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of beta-Bromo-beta-nitrostyrene 10245-W

CASRN: 7166-19-0

Formula: C8-H6-Br-N-O2

Synonyms/Common Names

  • Benzene, (2-bromo-2-nitroethenyl)-

Short-Term Toxicity

  • 4 weeks (Gavage)  (C60855)  Completed 
    • TOX-40 (NIH Number: 94-3389)  (Tox Peer Review 01/00/1994A )
      Toxicity Studies of beta-Bromo-beta-Nitrostyrene (CASRN 7166-19-0) Administered by Gavage to F344/N Rats and B6C3F1 Mice
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M 0, 0.037, 0.075, 0.3, 0.15, 0.6 G/KG; 10/GRP.

Special Studies

  • Absorption Distribution Metabolism Excretion (Gavage; Intravenous)  (S0088)  Completed 
    • Male Rats [R]: F344/N; Rats [R]: F344/N
    • Dose: (gavage) 1, 1.2, 10, 12, 98, 120 mg/kg [R]. (intravenous) 9.1-9.7 mg/kg [R].

Genetic Toxicology

  • Micronucleus  (A05982)  Completed 
    • Mice: B6C3F1
    • Male Positive 
    • Female Negative 
  • Micronucleus  (A40359)  Completed 
    • Rats: Fischer 344
    • Male Negative 
  • Micronucleus  (A43432)  Completed 
    • Rats: Fischer 344
    • Male Negative 
  • Salmonella  (535038)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K. Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals. Environ Mol Mutagen. 1992;19 Suppl 21:2-141. doi: 10.1002/em.2850190603
    •  Positive