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Testing Status of Dichlorodiphenyltrichloroethane (DDT) 10352-X

CASRN: 50-29-3

Formula: C14-H9-Cl5

Synonyms/Common Names

  • Benzene, 1,1'-(2,2,2-trichloroethylidene)bis(4-chloro-
  • Chlorophenothan
  • DDT
  • 4,4'-DDT

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C00464)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C00464)  Completed 
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Dose: R: 0, 178, 1780, M: 0, 18, 178 PPM/5 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C00464)  Completed 
    • TR-131 (NIH Number: 78-1386)  (Peer Review Approval 06/29/1978A )
      Bioassays of DDT, TDE, and p,p'-DDE for Possible Carcinogenicity (CASRN 50-29-3, CASRN 72-54-8, CASRN 72-55-9)
    • Rats: Osborne Mendel; Mice: B6C3F1
    • Dose: MR: 0, 321, 642 (AVG), FR: 0, 210, 420 (AVG), MM: 0, 22, 44 (AVG), FM: 0, 87, 175 (AVG) PPM/50 PER GROUP.
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Negative 
      • Male Mice Negative 
      • Female Mice Negative 

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (868203)  Completed 
    • Sister Chromatid Exchange Negative 
    • Chromosome Aberrations Negative 
  • Mouse Lymphoma  (836226)  Completed 
    • Mice
    •  Negative 
  • Salmonella  (873088)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K. Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals. Environ Mol Mutagen. 1992;19 Suppl 21:2-141. doi: 10.1002/em.2850190603
    •  Negative