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Testing Status of Fenthion 10362-F

CASRN: 55-38-9

Formula: C10-H15-O3-P-S2

Synonyms/Common Names

  • O,O-Dimethyl-O-(3-methyl-4-(methylthio)phenyl)phosphorothioic acid ester (9CI)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C08651)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C08651)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 5, 320 PPM/10 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C08651)  Completed 
    • TR-103 (NIH Number: 79-1353)  (Peer Review Approval 10/25/1978A )
      Bioassay of Fenthion for Possible Carcinogenicity (CASRN 55-38-9)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 10, 20 PPM/50 PER GROUP.
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Negative 
      • Male Mice Equivocal 
      • Female Mice Negative 

Genetic Toxicology

  • In Vitro Cytogenetics (CA/SCE)  (574321)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Negative 
  • Salmonella  (643396)  Completed 
    • Citation: Mortelmans K, Haworth S, Lawlor T, Speck W, Tainer B, Zeiger E. Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals. Environ Mutagen. 1986;8 Suppl 7:1-119
    •  Negative 
  • Salmonella  (909289)  Completed 
    • Citation: Mortelmans K, Haworth S, Lawlor T, Speck W, Tainer B, Zeiger E. Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals. Environ Mutagen. 1986;8 Suppl 7:1-119
    •  Weakly Positive