Skip to Main Navigation
Skip to Page Content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Testing Status of tert-Butyl hydroperoxide 10405-A

 

CASRN: 75-91-2

Formula: C4-H10-O2

Synonyms/Common Names

  • Cadox TBH
  • 1,1-Dimethylethylhydroperoxide
  • 2-Hydroperoxy-2-methylpropane
  • Luperox TBH70

Short-Term Toxicity

  • 14 days (Topical Application)  (C20215)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0, 22, 44, 88, OR 175 MG/KG M: 0, 22, 44, 88, 175, OR 350 MG/KG; 5/SEX/SPECIES.
  • 14 days (Gavage)  (C20215B)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0, 22, 44, 88, 175 OR 350 MG/KG; 5/SEX/SPECIES.

Genetic Toxicology

  • Drosophila  (376373)  Completed 
    • Citation: Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
    • Sex-Linked Recessive Lethal Positive 
    • Reciprocal Translocation Negative 
  • In Vitro Cytogenetics (CA/SCE)  (389785)  Completed 
    • Sister Chromatid Exchange Positive 
    • Chromosome Aberrations Positive 
  • Salmonella  (603477)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Positive 

Organ Systems Toxicity

  • varies Immunotoxicity (Topical Application)  (IMM20605)  Completed 
    • Female Mice: BALB/c
    • Dose: 0, 0.5, 1, 2.5, 5, 10, or 25%.