Testing Status of Anilazine 10483-F
CASRN: 101-05-3
Formula: C9-H5-Cl3-N4
Synonyms/Common Names
- 4,6-Dichloro-N-(2-chlorophenyl)-1,3,5-triazin-2-amine
- 2,4-Dichloro-6-O-Chloranilino-S-Triazine
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C08684)
Completed
- Rats: F344/N; Mice: B6C3F1
- 13-Week (Dosed-Feed)
(C08684)
Completed
- Rats: F344/N; Mice: B6C3F1
Long-Term Carcinogenicity
- 2-Year (Dosed-Feed)
(C08684)
Completed
- TR-104 (NIH Number: 78-1354)
(Peer Review Approval 06/29/1978A )
Bioassay of Anilazine for Possible Carcinogenicity (CASRN 101-05-3) - Rats: F344/N; Mice: B6C3F1
- Dose: 0, 500, 1000 PPM.
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- TR-104 (NIH Number: 78-1354)
(Peer Review Approval 06/29/1978A )
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(443411)
Completed
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Negative
- Mouse Lymphoma
(G52321)
Completed
- Citation: Myhr BC, Caspary WJ. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ Mol Mutagen. 1988;12 Suppl 13:103-94. doi: 10.1002/em.2860120505
- Mice
- Mouse Lymphoma
(G87759)
Completed
- Citation: Mitchell AD, Rudd CJ, Caspary WJ. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: intralaboratory results for sixty-three coded chemicals tested at SRI International. Environ Mol Mutagen. 1988;12 Suppl 13:37-101. doi: 10.1002/em.2860120504
- Mice
- Salmonella
(915261)
Completed
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
- Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K. Salmonella mutagenicity tests: IV. Results from the testing of 300 chemicals. Environ Mol Mutagen. 1988;11 Suppl 12:1-157
- Negative
- Salmonella
(N-9284)
Completed
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
- Citation: Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli Environ. Mutagen. Vol. 7 (Suppl 5) (1985) 1-248