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Testing Status of Isocyanuric acid 10526-A

CASRN: 108-80-5

Formula: C3-H3-N3-O3

Synonyms/Common Names

  • Cyanuric acid
  • 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione (9CI)
  • Tricarbimide

Special Studies

  • Toxicokinetic Study (Gavage)  (K10526)  Completed 
    • Citation: Jacob CC, Von Tungeln LS, Vanlandingham M, Beland, FA, Gamboa da Costa G. Pharmacokinetics of melamine and cyanuric acid and their combinations in F344 rats. Toxicol Sci. 2012 Apr;126(2):317-24. doi: 10.1093/toxsci/kfr348. Epub 2012 Jan 6.Pubmed Abstract
    • Male and Female Rats [R]: Fischer 344
    • Dose: (gavage) 1 mg/kg [R].
  • Toxicokinetic Study (Gavage; Intravenous)  (K10526B)  Completed 
    • Citation: Jacob CC, Von Tungeln LS, Vanlandingham M, Beland, FA, Gamboa da Costa G. Pharmacokinetics of melamine and cyanuric acid and their combinations in F344 rats. Toxicol Sci. 2012 Apr;126(2):317-24. doi: 10.1093/toxsci/kfr348. Epub 2012 Jan 6.Pubmed Abstract
    • Male and Female Rats [R]: F344 (NCTR)
    • Dose: (gavage) 1 mg/kg [R]. (intravenous) 1 mg/kg [R].

Genetic Toxicology

  • Salmonella  (599477)  Completed 
    • Citation: Haworth S, Lawlor T, Mortelmans K, Speck W, Zeiger E. Salmonella mutagenicity test results for 250 chemicals. Environ Mutagen. 1983;5 Suppl 1:1-142
    •  Negative