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Testing Status of Isocyanuric acid 10526-A

 

CASRN: 108-80-5

Formula: C3-H3-N3-O3

Synonyms/Common Names

  • Cyanuric acid
  • 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione (9CI)
  • Tricarbimide

Special Studies

  • Toxicokinetic Study (Gavage)  (K10526)  Completed 
    • Citation: Jacob CC, Von Tungeln LS, Vanlandingham M, Beland, FA, Gamboa da Costa G. Pharmacokinetics of melamine and cyanuric acid and their combinations in F344 rats. Toxicol Sci. 2012 Apr;126(2):317-24. doi: 10.1093/toxsci/kfr348. Epub 2012 Jan 6.Pubmed Abstract
    • Male and Female Rats: Fischer 344
    • Dose: 1 mg/kg.
  • Toxicokinetic Study (Gavage; Intravenous)  (K10526B)  Completed 
    • Citation: Jacob CC, Von Tungeln LS, Vanlandingham M, Beland, FA, Gamboa da Costa G. Pharmacokinetics of melamine and cyanuric acid and their combinations in F344 rats. Toxicol Sci. 2012 Apr;126(2):317-24. doi: 10.1093/toxsci/kfr348. Epub 2012 Jan 6.Pubmed Abstract
    • Male and Female Rats: F344 (NCTR)
    • Dose: 1 mg/kg.

Genetic Toxicology

  • Salmonella  (599477)  Completed 
    • Citation: Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
    •  Negative