Testing Status of 2-Chloroethyltrimethylammonium chloride 10669-Y
CASRN: 999-81-5
Formula: C5-H13-Cl-N.Cl
Synonyms/Common Names
- Chlorcholine chloride
- 2-Chloro-N,N,N-trimethylethanaminium chloride
Short-Term Toxicity
- 14-Day (Dosed-Feed)
(C02960)
Completed
- Rats: F344/N; Mice: B6C3F1
- 13-Week (Dosed-Feed)
(C02960)
Completed
- Rats: F344/N; Mice: B6C3F1
- Dose: R: 0, 3150, 14700, M: 0, 1200, 20000 PPM/5 PER GROUP.
Long-Term Carcinogenicity
- 135 weeks (Dosed-Feed)
(C02960)
Completed
- TR-158 (NIH Number: 79-1714)
(Peer Review Approval 12/13/1978A )
Bioassay of (2-Chloroethyl)trimethylammonium Chloride (CCC) for Possible Carcinogenicity (CASRN 999-81-5) - Rats: F344/N; Mice: B6C3F1
- Dose: R: 0, 1500, 3000, M: 0, 500, 2000 PPM/50 PER GROUP.
- Carcinogenesis Results
- Male Rats Negative
- Female Rats Negative
- Male Mice Negative
- Female Mice Negative
- TR-158 (NIH Number: 79-1714)
(Peer Review Approval 12/13/1978A )
Genetic Toxicology
- In Vitro Cytogenetics (CA/SCE)
(022395)
Completed
- Sister Chromatid Exchange Positive
- Chromosome Aberrations Negative
- In Vitro Cytogenetics (CA/SCE)
(564198)
Completed
- Sister Chromatid Exchange Negative
- Chromosome Aberrations Negative
- Mouse Lymphoma
(899913)
Completed
- Mice
- Negative
- Salmonella
(698498)
Completed
- Citation: Mortelmans K, Haworth S, Lawlor T, Speck W, Tainer B, Zeiger E. Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals. Environ Mutagen. 1986;8 Suppl 7:1-119
- Negative
- Salmonella
(752647)
Completed
- Citation: Mortelmans K, Haworth S, Lawlor T, Speck W, Tainer B, Zeiger E. Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals. Environ Mutagen. 1986;8 Suppl 7:1-119
- Negative