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Testing Status of Locust bean gum 10753-X

CASRN: 9000-40-2

Synonyms/Common Names

  • Carob gum (9CI)

Short-Term Toxicity

  • 14-Day (Dosed-Feed)  (C50419)  Completed 
    • Rats: F344/N; Mice: B6C3F1
  • 13-Week (Dosed-Feed)  (C50419)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 6300, 100000 PPM/10 PER GROUP.

Long-Term Carcinogenicity

  • 2-Year (Dosed-Feed)  (C50419)  Completed 
    • TR-221 (NIH Number: 82-1777)  (Peer Review Approval 10/15/1980A )
      Carcinogenesis Bioassay of Locust Bean Gum (CASRN 9000-40-2) in F344 Rats and B6C3F1 Mice (Feed Study)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: 0, 25000, 50000 PPM/50 PER GROUP.
    • Carcinogenesis Results
      • Male Rats Negative 
      • Female Rats Negative 
      • Male Mice Negative 
      • Female Mice Negative 

Genetic Toxicology

  • Salmonella  (945885)  Completed 
    • Citation: Zeiger E, Anderson B, Haworth S, Lawlor T, Mortelmans K. Salmonella mutagenicity tests: V. Results from the testing of 311 chemicals. Environ Mol Mutagen. 1992;19 Suppl 21:2-141. doi: 10.1002/em.2850190603
    •  Negative