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Testing Status of Ozone 10957-Y

CASRN: 10028-15-6

Formula: O3

Synonyms/Common Names

  • Triatomic oxygen

Short-Term Toxicity

  • 4 weeks (Inhalation)  (C88034)  Completed 
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 0.5, OR 1.0 PPM (5/SEX/SPECIES/GROUP).

Long-Term Carcinogenicity

  • 2 years (Inhalation)  (C88034)  Completed 
    • TR-440 (NIH Number: 95-3371)  (Peer Review Approval 11/16/1993A )
      Toxicology and Carcinogenesis Studies of Ozone (CASRN 10028-15-6) and Ozone/NNK (CASRNs 10028-15-6/64091-91-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 0.12, 0.5, OR 1.0 PPM (50/SEX/SPECIES/GROUP).
    • Carcinogenesis Results
      • Male Rats No Evidence 
      • Female Rats No Evidence 
      • Male Mice Equivocal Evidence 
      • Female Mice Some Evidence 
  • Lifetime (Inhalation)  (C88034B)  Completed 
    • TR-440 (NIH Number: 95-3371)  (Peer Review Approval 11/16/1993A )
      Toxicology and Carcinogenesis Studies of Ozone (CASRN 10028-15-6) and Ozone/NNK (CASRNs 10028-15-6/64091-91-4) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R&M: 0, 0.5, OR 1.0 PPM (50/SEX/SPECIES/GROUP).
    • Carcinogenesis Results
      • Male Rats No Evidence 
      • Female Rats No Evidence 
      • Male Mice Equivocal Evidence 
      • Female Mice Some Evidence 

Genetic Toxicology

  • Salmonella  (A31529)  Completed 
    •  Positive