Testing Status of Dibromoacetonitrile 10985-P

CASRN: 3252-43-5

Formula: C2-H-Br2-N

Synonyms/Common Names

• Dibromoacetonitrile

Special Studies

• Absorption Distribution Metabolism Excretion (Gavage; Intravenous; Gavage; Intravenous)  (S0820)  Completed 
  • Male Rats [R]: F344/N; Male Mice [M]: B6C3F1
  • Dose: (all routes) 0.2, 2 and 20 mg/kg [R,M].

Genetic Toxicology

• Drosophila  (369991)  Completed 
  • Citation: Valencia R, Mason JM, Woodruff RC, Zimmering S. Chemical mutagenesis testing in Drosophila. III. Results of 48 coded compounds tested for the National Toxicology Program. Environ Mutagen. 1985;7(3):325-48. doi: 10.1002/em.2860070309
  • Reciprocal Translocation/Sex-Linked Recessive Lethal Negative 
• Micronucleus  (A00107)  Completed 
  • Mice: B6C3F1
  • Male Negative 
  • Female Negative 
• Salmonella  (298559)  Completed 
  • Citation: Mortelmans K, Haworth S, Lawlor T, Speck W, Tainer B, Zeiger E. Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals. Environ Mutagen. 1986;8 Suppl 7:1-119
  •  Weakly Positive 
• Salmonella  (450116)  Completed 
  •  Weakly Positive 
• Salmonella  (573952)  Completed 
  •  Equivocal 
• Salmonella  (877154)  Completed 
  • Citation: Mortelmans K, Haworth S, Lawlor T, Speck W, Tainer B, Zeiger E. Salmonella mutagenicity tests: II. Results from the testing of 270 chemicals. Environ Mutagen. 1986;8 Suppl 7:1-119
  •  Weakly Positive 
• Salmonella  (A44565)  Completed 
  •  Positive 

Organ Systems Toxicity

• 35 days Repro/Dev Gen Tox (28-Day) (Dosed-Water)  (RDGT94014)  Completed 
  • Male and Female Rats: Sprague Dawley
  • Dose: 0, 15, 50, OR 150 PPM.