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Testing Status of Cupric sulfate 7758998

CASRN: 7758-99-8

Formula: Cu.H2-O4-S.5H2-O

Synonyms/Common Names

  • Copper sulfate
  • Sulfuric acid copper(2+) salt (1:1), pentahydrate

Short-Term Toxicity

  • 2 weeks (Dosed-Water)  (C62191)  Completed 
    • TOX-29 (NIH Number: 93-3352)  (Peer Review Approval 12/00/1992A )
      Toxicity Studies of Cupric Sulfate (CASRN 7758-99-8) Administered in Drinking Water and Feed to F344/N Rats and B6C3F1 Mice
    • Rats: F344/N; Mice: B6C3F1
  • 2 weeks (Dosed-Feed)  (C62191B)  Completed 
    • TOX-29 (NIH Number: 93-3352)  (Peer Review Approval 12/02/1992A )
      Toxicity Studies of Cupric Sulfate (CASRN 7758-99-8) Administered in Drinking Water and Feed to F344/N Rats and B6C3F1 Mice
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R& M: 0, 1000, 2000, 4000, 8000, 16000 PPM (5/S/S).
  • 13 weeks (Dosed-Feed)  (C62191B)  Completed 
    • TOX-29 (NIH Number: 93-3352)
      Toxicity Studies of Cupric Sulfate (CASRN 7758-99-8) Administered in Drinking Water and Feed to F344/N Rats and B6C3F1 Mice
    • Rats: F344/N; Mice: B6C3F1
    • Dose: R: 0, 500, 1000, 2000, 4000, 8000 PPM M: 0, 1000, 2000, 4000, 8000, 16000 PPM (10/S/S).

Special Studies

  • C. elegans  (S0948)  Completed 
    • C. elegans [CE]

Genetic Toxicology

  • Micronucleus  (A61262)  Completed 
    • Citation: Witt KL, Knapton A, Wehr CM, Hook GJ, Mirsalis J, Shelby MD, MacGregor JT. Micronucleated erythrocyte frequency in peripheral blood of B6C3F(1) mice from short-term, prechronic, and chronic studies of the NTP carcinogenesis bioassay program. Environ Mol Mutagen. 2000;36(3):163-94
    • Mice: B6C3F1
    • Male Equivocal 
    • Female Negative