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Testing Status of Juglone M000012

CASRN: 481-39-0

Formula: C10-H6-O3

Synonyms/Common Names

  • Akhnot
  • C.I. Natural Brown 7
  • 1,4-Napthoquinone, 5-hydroxy-(8CI)
  • Regianin
  • Walnut extract

Special Studies

  • Absorption Distribution Metabolism Excretion (Gavage; Topical Application; Intravenous)  (S0838)  Completed 
    • Citation: Chen LJ, Lebetkin EH, Burka LT. Metabolism and disposition of juglone in male F344 rats. Xenobiotica. 2005 Oct-Nov;35(10-11):1019-34.Pubmed Abstract
    • Male Rats [R]: F344/N
    • Dose: (gavage) 0.1, 1.0, 10 mg/kg [R]. (topical application) 4 mg/kg [R]. (intravenous) 0.1 mg/kg [R].
  • C. elegans  (S0953)  Completed 
    • C. elegans [CE]

Genetic Toxicology

  • Salmonella  (A50290)  Completed 
    •  Positive