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Testing Status of Nanoscale material (Quantum dots) M040086


Synonyms/Common Names

  • Quantum dots (Nanoscale materials)

Short-Term Toxicity

  • 2 weeks (Topical Application)  (C20409)  Completed 
    • Mice: SKH-1 Hairless (NCTR)
    • Dose: M1.

Special Studies

  • Toxicokinetic Study (Subcutaneous Injection; Topical Application; Intradermal Injection)  (S0918)  Completed 
    • Citation: Gopee NV, Roberts DW, Webb P, Cozart CR, Siitonen PH, Latendresse JR, Warbitton AR, Yu WW, Colvin VL, Walker NJ, Howard PC. Quantitative determination of skin penetration of PEG-coated CdSe quantum dots in dermabraded but not intact SKH-1 hairless mouse skin. Toxicol Sci. 2009 Sep;111(1):37-48. doi: 10.1093/toxsci/kfp139. Epub 2009 Jul 2.Pubmed Abstract
    • Mice [M]: SKH-1 Hairless; Female Mice [M]: SKH-1 Hairless (NCTR); Mice [M]
    • Dose: (all routes) 0, 4, 8 and 24 hour intervals w/ various mice per group [M]. (intradermal injection) 48 pmol [M].