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Testing Status of Raloxifene hydrochloride M060066


CASRN: 82640-04-8

Formula: C28-H27-N-O4-S.Cl-H

Synonyms/Common Names

  • 6-Hydroxy-2-(p-hydroxyphenyl)benzo(b)thien-3-yl-p-(2-piperidinoethoxy)phenyl ketone, hydrochloride
  • Keoxifene hydrochloride

Short-Term Toxicity

  • 14 days (Gavage)  (C06066)  On Test 
    • Rats: Hsd:Sprague Dawley SD
    • Dose: 0, 1, 3, 10, 30, 100 mg/kg.
  • 1 day (Gavage)  (C06066B)  On Test 
    • Series Dose Escalation Cardiovascular Functional Assessment Study
    • Rats: Hsd:Sprague Dawley SD
    • Dose: Dose escalation, Single dose + recovery per dose level 0, 1, 3, 10, 30, 100 mg/kg.